… ;Cx43 fx/fx ;Cx37 −/− mice, we tested our method on lymphatic valves displaying a wide range
… -leak or valve stiffness in the absence of pressure measurement/control. Without pressure …

… we examined EC polarization in the presence and absence of Cx37. Because we thought that
… The Cx37-null mouse lacks the aspect of abnormal mechanotransduction that is present in …

… , Cx37 is growth suppressive at cell densities where gap junction channels cannot form due
to lack of cell… Cardiac malformation in neonatal mice lacking connexin43. Science. 1995;267(…

… Cx37 is not changed, suggesting posttranslational effects. It was speculated that the lack of
… , thus leading exclusively to formation of Cx37 that may be less stable than heteromers (436)…

… connexin37 and connexin43 (both required for normal valve development) around reorientating
valve-forming cells and produced deficient valve… because of a lack of specific antibodies, …

… to venous valves (17). Genetic ablation of Cx37 and Cx43 leads to lymphatic valve malforma…
either knockout or wildtype mice, thus a lack of regional protein expression may explain the …

… Traditional lymphatic vessels are absent from the medulla of kidneys. However, … , venous
valves and cardiac valves share significant molecular similarities with lymphatic valves [42,43,…

… Likewise, lacking Cx45 in mice predisposes to embryonic … linked Cx37 deficiency to both
venous and lymphatic valve … ’s father with lone AF, but absent in the unaffected family members …

… We recently demonstrated that, in the absence of RASA1, EC are unable to export the …
developmental, neonatal and pathological angiogenic responses in the absence of RASA1. …

… valve development, we aimed to delete Prox1 specifically from VECs by using the Prox1 f/f
mice without … In contrast, PROX1 high lymphatic capillaries and lymphatic valves lack PDGF-B …